Bernhard Lämmle Selected Research

Prekallikrein

1/2021	c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans.
1/2020	Severe plasma prekallikrein deficiency: Clinical characteristics, novel KLKB1 mutations, and estimated prevalence.
4/2002	Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
3/2002	Prekallikrein deficiency: the characteristic normalization of the severely prolonged aPTT following increased preincubation time is due to autoactivation of factor XII.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Bernhard Lämmle Research Topics

Disease

47	Thrombotic Thrombocytopenic Purpura 02/2021 - 01/2002
22	Thrombocytopenia (Thrombopenia) 02/2021 - 01/2002
14	Thrombotic Microangiopathies 02/2021 - 07/2002
11	Hemolytic-Uremic Syndrome 09/2013 - 01/2002
9	Hemorrhage 01/2017 - 03/2002
8	Hemolytic Anemia 02/2021 - 09/2003
8	acquired Thrombotic thrombocytopenic purpura 11/2014 - 04/2002
7	Thrombosis (Thrombus) 01/2021 - 08/2008
6	Neoplasms (Cancer) 08/2021 - 01/2004
4	Venous Thromboembolism 01/2018 - 01/2015
4	Anemia 01/2017 - 11/2014
4	Hemolysis 03/2016 - 01/2005
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2015 - 08/2005
4	Diarrhea 11/2010 - 01/2002
4	Sepsis (Septicemia) 03/2008 - 07/2002
3	Disease Progression 01/2021 - 01/2002
3	Pyruvate Kinase Deficiency of Red Cells 01/2021 - 03/2002
3	Inflammation (Inflammations) 01/2018 - 07/2003
3	Renal Insufficiency (Renal Failure) 03/2016 - 09/2003
3	Pre-Eclampsia (Preeclampsia) 08/2015 - 03/2014
3	Hypertension (High Blood Pressure) 01/2015 - 12/2003
3	Septic Shock (Toxic Shock Syndrome) 01/2007 - 07/2002
3	Fever (Fevers) 01/2004 - 07/2003
2	COVID-19 02/2021 - 01/2021
2	Disseminated Intravascular Coagulation 02/2021 - 12/2009
2	Fatigue 01/2020 - 06/2009
2	Rare Diseases (Rare Disease) 10/2019 - 09/2007
2	Pulmonary Embolism 09/2019 - 01/2015
2	Diabetes Mellitus 01/2017 - 01/2015
2	Infections 01/2015 - 08/2012
2	HIV Infections (HIV Infection) 03/2012 - 04/2009
2	Venous Thrombosis (Deep-Vein Thrombosis) 08/2011 - 01/2011
2	Ischemic Stroke 01/2010 - 12/2003
1	Reperfusion Injury 08/2021
1	Salmonella Infections (Salmonellosis) 01/2021
1	Atherosclerosis 01/2021
1	Iron Deficiencies 01/2020
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2019
1	Postpartum Hemorrhage 09/2018
1	Leukocytosis (Pleocytosis) 01/2018
1	Cognitive Dysfunction 05/2017
1	Atypical Hemolytic Uremic Syndrome 03/2016

Drug/Important Bio-Agent (IBA)

43	thiamine triphosphorate (TTP)IBA 02/2021 - 01/2002
14	AutoantibodiesIBA 01/2021 - 03/2004
14	von Willebrand FactorIBA 01/2021 - 01/2002
9	ADAMTS13 ProteinIBA 08/2015 - 04/2002
7	Metalloproteases (Metalloproteinases)IBA 01/2021 - 08/2005
6	EnzymesIBA 01/2021 - 07/2003
6	ThrombospondinsIBA 01/2021 - 08/2005
6	AntibodiesIBA 01/2020 - 05/2003
5	DisintegrinsIBA 01/2021 - 08/2005
5	Heparin (Liquaemin)FDA LinkGeneric 01/2012 - 07/2002
4	PrekallikreinIBA 01/2021 - 03/2002
4	Hemoglobins (Hemoglobin)IBA 01/2020 - 01/2005
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 03/2008
3	C-Reactive ProteinIBA 09/2019 - 01/2017
3	Prothrombin (Factor II)IBA 10/2017 - 12/2003
3	fibrin fragment D (D-dimer)IBA 01/2017 - 03/2009
3	AntigensIBA 11/2014 - 03/2002
3	Platelet Factor 4IBA 01/2012 - 05/2003
2	Fibrinogen (Factor I)FDA Link 02/2021 - 12/2003
2	Factor VIII (Coagulation Factor VIII)IBA 01/2021 - 01/2011
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2018 - 01/2007
2	Rituximab (Mabthera)FDA Link 10/2018 - 09/2007
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 08/2012
2	factor V LeidenIBA 10/2017 - 12/2005
2	Complement System Proteins (Complement)IBA 03/2016 - 05/2003
2	Vitamin K FDA Link 01/2015 - 08/2011
2	EpitopesIBA 02/2012 - 06/2004
2	AntithrombinsIBA 08/2011 - 03/2009
2	Immunoglobulins (Immunoglobulin)IBA 01/2011 - 01/2005
2	Indicators and Reagents (Reagents)IBA 03/2008 - 03/2002
2	High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA 03/2008 - 04/2002
2	Blood Coagulation Factors (Coagulation Factor)IBA 11/2006 - 12/2003
2	ImmunosorbentsIBA 08/2005 - 07/2003
2	Hemostatics (Antihemorrhagics)IBA 12/2003 - 04/2002
2	Factor XII (Hageman Factor)IBA 04/2002 - 03/2002
1	Biological ProductsIBA 08/2021
1	Dacarbazine (DIC)FDA LinkGeneric 02/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	Ferritins (Ferritin)IBA 01/2020
1	Kininogens (Kininogen)IBA 01/2020
1	IronIBA 01/2020
1	pro-brain natriuretic peptide (1-76)IBA 09/2019
1	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2019
1	Troponin T (Troponin T1)IBA 09/2019
1	A-factor (Streptomyces)IBA 10/2017
1	Oxymorphone (Numorphan)FDA LinkGeneric 01/2017
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2017
1	IntegrinsIBA 01/2017
1	TroponinIBA 01/2017
1	caplacizumabIBA 05/2016

Therapy/Procedure

6	Therapeutics 09/2018 - 01/2004
6	Plasma Exchange 12/2012 - 07/2003
4	Hematopoietic Stem Cell Transplantation 01/2019 - 01/2004
2	Polypharmacy 01/2017 - 01/2015
2	Splenectomy 03/2004 - 01/2004
1	Operative Surgical Procedures 01/2021
1	Length of Stay 01/2016